For most people, it seems that just as they get through the stage of worrying over acne, they enter into the phase of seeing wrinkles and age spots crop up. While wrinkles are a natural part of aging, caused by changes in the skin composition, that’s just it…Thinner, drier, more wrinkled skin is a telltale sign of one’s age. Wrinkles can appear anywhere, but they’re most common in the parts of the face where the muscles are repeatedly used, such as around the mouth and eyes. If you’re concerned about your frown lines giving way to your age or you just have a few pesky wrinkles you’d like to get rid of, consider this list of the best deep wrinkle cream for frown lines.

1. Peter Thomas Roth Un-Wrinkle Turbo Face Serum

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Peter Thomas Roth Un Wrinkle Turbo, 1 Fluid Ounce
  • A high-performance anti-wrinkle treatment
  • Contain a turbo-charged blend of 18 potent anti-aging neuropeptides and peptides
  • Helps banish the six most stubborn deep wrinkles and facial expression lines

If the name doesn’t give it away with this one, then nothing will. Seriously, though, the Peter Thomas Roth Un-Wrinkle Turbo Face Serum stands up to its name and really is a supercharged wrinkle fighter and one of the best deep wrinkle cream for frown lines. The formula is made with a unique blend of 18 neuropeptides and peptides to target deep lines and wrinkles and lift them. This peptide complex effectively stimulates collagen production for even better results over time, yet it is still safe and gentle enough even for a more mature skin.

Major Benefits

  • Proprietary blend of 18 neuropeptides and peptides.
  • Safe and effective even for sensitive, mature skin.
  • Improves skin volume and smooths texture.
  • Provides antioxidants and vitamins C & E.
  • Improves skin hydration with hyaluronic acid.

2. Neutrogena Rapid Wrinkle Repair Serum

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Neutrogena Rapid Wrinkle Repair Anti-Wrinkle Serum with Retinol, Hyaluronic Acid, and...
  • 1-fluid ounce tube of Neutrogena Rapid Wrinkle Repair Anti-Wrinkle Serum with Retinol. In...
  • Lightweight, silky retinol serum absorbs quickly to help smooth fine lines and texture,...
  • Retinol SA continuously renews skin, helping to smooth wrinkles fast and diminish the look...

With the reliability of Neutrogena, the Rapid Wrinkle Repair Serum is a great option for those looking for a simple solution to stubborn frown lines. This formula combines the power of retinol, in the form of vitamin A, with hyaluronic acid to both plump and moisturize the skin. The product is a great lightweight option that can be used as a daytime moisturizer to literally improve your skin all day long.

Major Benefits

  • Patented retinol, glucose complex, and hyaluronic acid formula.
  • Smooth lightweight feels perfect for all-day wear.
  • Moisturizes as it improves the appearance of lines and wrinkles.
  • Effective but gentle, non-irritating formulation, ideal for mature skin.

3. Frownies Facial Patches for Wrinkles on the Corner of Eyes & Mouth

Frownies Corners Of Eyes And Mouth, 144 Patches
  • Frownies are a simple method to reverse deep expression lines Frownies repair...
  • Dramatically reduce lines and wrinkles safely and naturally
  • Trains the underlying facial muscles to regain the strength and tone they have lost

You’ve likely heard of the facial exercises intended to improve facial wrinkles. Well, Frownies Facial Patches for Wrinkles are essentially the opposite but are much more effective, as the exercises essentially just create more lines and wrinkles. Frownies patches train your facial muscles to relax and situate your face in a non-expressive state while you’re sleeping to repair damage and reduce the appearance of deep wrinkles.

Major Benefits

  • Safe, effective method to relax facial muscles.
  • Unbleached, breathable paper to maximize benefits.
  • Hypoallergenic, non-GMO, plant-based adhesive.

4. iS Clinical Youth Complex with Innovase

Ideal for individuals 35 and over, the iS Clinical Youth Complex is an intensive serum that can dramatically improve the appearance of frown lines and other wrinkles and a definite contender as one of the best deep wrinkle cream for frown lines. The formula is a unique blend of white willow bark extract, copper tripeptide growth factor, hyaluronic acid, and mixed fruit acid extracts. These components work together to reduce inflammation throughout the skin while stimulating new collagen growth to reduce wrinkles over time.

Major Benefits

  • Reduces the appearance of lines and wrinkles as it smooths and softens.
  • Delivers immediate, intermediate, and long-term results.
  • Provides natural, paraben-free antioxidant protection.
  • Combines antioxidants, natural hydrators, and exclusive bio-complex.

5. Meaningful Beauty Ultra Lifting and Filling Treatment

Meaningful Beauty – Ultra Lifting & Filling Treatment – Melon Extract Day Serum – 1...
  • Formulated with our exclusive orchid extract
  • Helps leave skin looking firmer and more lifted
  • Contains no parabens

Ideal for women under 40, this Meaningful Beauty Treatment is a great pick for those who want to improve age-related changes in their skin and prevent any further issues. The formula combines a unique microencapsulated melon complex with hyaluronic acid, vitamin C, and glycerin to reduce inflammation, even skin tone, and plump and smooth wrinkles. The hyaluronic acid functions to deliver immediate results while also improving the appearance of frown lines over time with its ability to attract and hold on to moisture in the skin.

Major Benefits

  • Reduces inflammation with a powerful anti-inflammatory melon complex.
  • Promotes moisture and reduces lines and wrinkles effectively.

6. Obagi Hydrate Luxe Moisture-Rich Cream

Obagi Hydrate Luxe Moisture-Rich Cream, 1.7 oz.
  • Delivers deep skin hydration
  • Reduces the appearance of fine lines, wrinkles and enhances skin's smoothness
  • Skin is more radiant

A uniquely luxurious formula, the list of best deep wrinkle cream for frown lines wouldn’t be complete without Obagi Hydrate Luxe Moisture-Rich Cream. This product contains effective ingredients like hydromanil, glycerin, mango, shea, and avocado to moisturize and plump the skin for immediate results. This product also delivers more targeted results over time as its active ingredients work together to reduce inflammation and repair the skin.

Major Benefits

  • Increases moisture and plumps skin with hydromanil.
  • Contains galactomannans that increase moisture deep within the skin.
  • Reduces inflammation and repairs skin naturally.
  • Soothes and smooth skin for improved overall appearance.

7. Obagi Professional-C Serum

Obagi Professional-C Serum 20%, 1 fl. oz.
  • Designed to stimulate collage to firm and support skin
  • Superior delivery system, resulting in greater penetration to all layers of the skin
  • Lighten skin discolorations, moisturize and hydrate skin to improve both texture and tone

A highly concentrated vitamin C serum, Obagi Professional-C is ideal for those looking for skin brightening benefits in addition to reducing frown lines. This formula contains 20% vitamin C, which stimulates collagen production to plump even the deepest of frown lines. Even better, it can actually be used all over the skin to brighten it and improve skin tone.

Major Benefits

  • Stimulates collagen production to lift and firm skin.
  • Contains 20% vitamin C for safe, effective results.
  • Leaves skin feeling smooth, silky, and soft.

8. Dr. Dennis Gross C+ Collagen Deep Cream

Dr Dennis Gross C+ Collagen Deep Cream, 1.7 Ounce
  • Gives skin a dewy glow
  • Smoothens fine lines and wrinkles
  • Helps with fine lines, wrinkles and dark spots

A deeply hydrating formula, this C+ Collagen Deep Cream is a powerful combination of sunflower, rice bran, and camellia japonica seed oils that work together to moisturize and repair. The deep penetrating vitamin C complex in this formula also functions to promote collagen growth and naturally brightens the skin making it a great all-around product as well as one of the best deep wrinkle cream for frown lines. The blend also contains collagen amino acids that deliver immediate results and keep the benefits coming over time.

Major Benefits

  • Promotes collagen growth with powerful vitamin C formula and collagen amino acids.
  • Brightens and energizes skin to deliver a youthful allover glow.
  • Contains natural nourishing oils to repair the skin’s barrier and promote hydration.

Summing Up

Finding the best deep wrinkle cream for frown lines isn’t an easy task, especially if you have sensitive or mature skin. And the bottom line is if you want to reduce the appearance of your frown lines and wrinkles, you are going to have to work for it. But you don’t have to do all of the heavy liftings yourself. In fact, if you pick a product from this list, you can know that you’ll be getting a trustworthy product and one of the best deep wrinkle cream for frown lines nearly without lifting a finger.